Thr210
WebApr 11, 2024 · Interestingly, indirect analysis of PLK1 kinase activation as assessed by the PLK1 activatory phosphorylation at Thr210 (Macůrek et al, 2008) as well as by the PLK1 phospho-substrate BubR1 (Elowe et al, 2007; Fig 3H and I), suggested that depletion of UBAP2L leads to increased PLK1 kinase activity in interphase. WebNM_001130682.3(GUCY1A1):c.630C>T (p.Thr210=) AND not provided Clinical significance: Likely benign (Last evaluated: Apr 20, 2024) Review status: 1 star out of maximum of 4 stars
Thr210
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WebDescription: The PathScan® Phospho-PLK1 (Thr210) Sandwich ELISA Kit is a solid phase sandwich enzyme-linked immunosorbent assay (ELISA) that detects endogenous levels of … WebThr210 phosphorylation under these conditions and occurs well before entry into mitosis. To understand when exactly PLK1 kinase activity is first induced duringanongoingcellcycle, ...
WebSubstitution of Thr210 with Asp has been reported to elevate PLK1 kinase activity and delay/arrest cells in mitosis, while a Ser137Asp substitution leads to S-phase arrest (12). … WebAdditionally, the protein levels of pPlk1(Ser137) and pPlk1(Thr210), as well as the subcellular distribution of pPlk1(Thr210), were not affected by BI2536. Taken together, …
WebDetect and quantitate cellular phospho-PLK1 (Thr210) using a homogeneous AlphaLISA® SureFire® Ultra™ assay. We are now two standalone organizations Life Sciences & … WebKind Code: A1 Abstract: Antibodies that specifically bind to one or more epitopes within human sortilin or mammalian sortilin are provided. Kind Code: A1 An isolated anti-Sortilin …
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