WebAnalysis of circulating miRNAs (cmiRNAs) before surgical operation (BSO) and after the surgical operation (ASO) has been informative for lung adenocarcinoma (LUAD) diagnosis, progression, and outcomes of treatment. Thus, we performed a biological WebFax +86 020 85223271. Email [email protected]; [email protected]. Purpose: Bone metastasis is one of the common causes of death relative to breast cancer. However, the evolvement of bone niche in cancer progression remains poorly understood. A three-dimensional (3D) engineered bone matrix was developed as an effective biomimetic …
TGIF1 Gene - GeneCards TGIF1 Protein TGIF1 Antibody
WebFurthermore, blockage of the AKT pathway enhanced ATO-induced CDKN1A expression and resultant apoptosis in cancer cells, but overexpression of AKT1 inhibited CDKN1A expression. Therefore, we suggest that TGIF is transcriptionally regulated by the c-Src/EGFR/AKT pathway, which plays a role as a negative regulator in antagonizing ATO … WebConclusion: We propose that the lack of Tgif1 in osteoblasts increases Sema3E expression and attenuates breast cancer cell migration as well as metastases formation. Keywords: Breast cancer, Bone metastases, Osteoblasts, Tgif1 Background Breast cancer is one of the most prevalent malignancies and constitutes a tremendous medical and socio- illinois high school tennis rankings
TGIF1 repressed TGF-β-induced gene expression independently of …
Web9 Apr 2024 · In vivo deletion of Tgif1 in mice attenuates the progression of bone metastases and protects from breast cancer-induced bone destruction. Together, our findings establish osteoblasts and Tgif1 as important regulators of breast cancer cells in the bone microenvironment and of the formation of breast cancer bone metastases. Methods Cell … Web24 Jun 2015 · Transforming growth factor beta-inducing factor 1 (TGIF1) was reported to be dysregulated in several types of cancer. However, its expression pattern and functions in nonsmall cell lung cancer (NSCLC) remained unknown. In the present study, the expression of TGIF1 was found to be elevated in the clinical NSCLC tissues. WebExpression of TGIF1 (HPE4, TGIF) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. illinois high schools ranked